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One Year Later, Spierer\'s Parents Cling to Hope

A full year after a 20-year-old Indiana University student disappeared from her college town, the woman's parents are down to just “this little bit of hope” she could still be alive.

“It's a remote possibility that she's alive and a greater possibility that she's not,” said Robert Spierer, whose daughter, Lauren, disappeared early Friday, June 3, 2011, near the school's Bloomington campus.

“It's a remote possibility that she's alive and a greater possibility that she's not.”

- Robert Spierer, father of missing co-ed

Spierer, of Greenburgh , N.Y., was last seen early that morning on the intersection of 11th Street and College Avenue in Bloomington, according to the woman's acquaintance and college classmate Jay Rosenbaum.

Rosenbaum claims he watched the petite, blonde-haired student walk from his building toward her off-campus apartment complex some three blocks away around 4:30 a.m. the morning she disappeared.

Rosenbaum's last reported sighting of Spierer followed a night of partying among a loose group of college friends and acquaintances.

Robert Spierer believes his daughter, who took medication for a heart condition, could have been drugged at Kilroy's Sports Bar, a popular college hangout with an outdoor sandy area designed to look like a beach. Authorities reported that Spierer left her shoes and cell phone behind there.

“She could have been given something in her drink, unknowingly, that made her almost incapacitated,” Robert Spierer told FoxNews.com.

Spierer, a fashion merchandising major who had just completed her sophomore year, left her apartment complex around 12:30 a.m. June 3 with a friend, David Rohn, to walk to Rosenbaum's apartment. Once at Rosenbaum's residence, Spierer met a male acquaintance â€" Corey Rossman â€" who lived two doors down from Rosenbaum.

Rossman, who was reportedly on a “no trespass” list at Spierer's building over a 2010 incident that had occurred there, left his building with Spierer and headed for Kilroy's Sports Bar. Police said Spierer and Rossman entered the bar at 1:46 a.m. and left at 2:27 a.m.

Many questions surround what happened next.

Surveillance video captured Rossman and Spierer entering her apartment building â€" known as Smallwood â€" shortly after leaving the bar. Rossman reportedly claimed he was injured in a fight with other male students on the fifth floor of the building and remembers nothing of what happened during and after the incident. At 2:42 a.m., Spierer is seen leaving her building with Rossman and walking up an alley toward Rosenbaum and Rossman's apartment complex.

Spierer, who police say dropped her keys and identification card on the way, spent some time at the men's building before leaving at 4:30 a.m., according to Rosenbaum, who claims he watched from a balcony as she walked toward her apartment. Spierer was never seen or heard from again.

Do the young men who last saw Spierer alive know her fate? Or did she fall victim to a stranger abduction as she walked in the dark, alone and inebriated, a short distance toward her home?    

Bo Dietl, a New York-based private investigator hired by the Spierer family, said “all options remain on the table.”

“At this point, no one has been eliminated,” Deitl told FoxNews.com. “Everyone is still a suspect as far as knowing what happened to Lauren.”

Robert Spierer and his wife, Charlene, say they believe the group of male students â€" including Rossman's roommate, Mike Beth â€" know more than what they've told investigators.

“Obviously we don't feel they've done everything in their power to be of assistance to us,” Robert Spierer said.

Spierer's disappearance touched off a massive search by air, land and water for any trace of the young woman. The Bloomington Police Department said Thursday it receives on average about two to three “credible” leads weekly in the case â€" totaling more than 2,600 tips to date.

Last August, the FBI scoured the Sycamore Ridge Landfill in Pimento for any clues in the case. Authorities are also probing a possible connection between Spierer and accused serial killer William Clyde Gibson, a 54-year-old convicted sex offender linked to the deaths of at least three women more than 100 miles away. The remains of one of the victims â€" 35-year-old mother Stephanie Kirk â€" were found buried in the backyard of Gibson's home in New Albany, Ind. Police have so far determined no connection between Spierer and Gibson.

Lauren, whom family described as “vivacious” and “loving,” had a an ability to “make everyone feel very comfortable,” her mother said.

Spierer, who is 4-foot-11 and weighs 95 pounds, has blonde hair and blue eyes. She was last seen wearing black pants and a white top.

A $250,000 reward is being offered for any information leading to Spierer's whereabouts. Anyone with tips in the case is urged to contact the Bloomington Police Department by phone at 812-339-4477 or by email at policetips@bloomington.in.gov.

To learn more about Spierer's disappearance, visit FindLauren.com



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Wisconsin Candidates Start Final Push Before Recall

  • Walker_recall.jpg

    Friday June 1, 2012: GOP Gov. Scott Walker campaigns at Miller Electric Greenville, Wis.AP

Republican Gov. Scott Walker and Democratic challenger Tom Barrett began a final push Saturday to connect with voters in person before next week's historic recall election, appearing at farm breakfasts and restaurants and rallying campaign workers.

Walker is only the third U.S. governor to face a recall. The drive to oust him was spurred by anger over his plan to effectively end most public workers' collective bargaining rights. Walker insisted he had to make the move to balance the state budget, but Democrats portrayed the measure as an attack on organized labor.

Polls show a tight race with only a handful of voters still undecided before Tuesday's election, and Walker and Barrett have been struggling to win them over for the past month. Barrett released a new television ad Saturday, again calling on the governor to explain his role in an ongoing investigation of associates during Walker's tenure as Milwaukee County executive, but the candidates mostly used the day to meet voters.

Barrett, who serves as Milwaukee's mayor, spent the day on the other side of the state, starting with the Barron County Dairy Breakfast in Hillsdale, a burg of 1,250 people about 90 miles west of Minneapolis. The rest of his schedule included stops at a cafe in St. Croix Falls, a pizza joint in Superior and the state Democratic Party's office in Chippewa Falls.

"We're going to cover the whole state here in the next four days," Barrett said in a telephone interview. "I love it. This is the part that really gets your juices flowing. This is where I'm most confident, doing this."

Walker began his day before 7 a.m., serving food at a dairy breakfast on a massive farm just outside Evansville, a city of 5,000 people about 25 miles south of Madison, the state capital. His agenda called for a stop at another dairy breakfast in Monroe County before visiting campaign field offices in Hudson, Wausau, Green Bay and Wauwatosa.

"I feel good," Walker said. "We're not taking anything for granted. We're working all the way up to 8 p.m. on Tuesday."

Dressed in blue jeans, hiking boots and a button-down shirt and flanked by 18-year-old Evansville Future Farmers of America Queen Emily Templeton and 18-year-old La Prairie 4-H Club Queen Erica Ballmer, the governor handed out yogurt and applesauce to scores of people at the annual Rock County Dairy Breakfast.

A smiling Walker tried to engage people in short, friendly conversations, commenting, for example, on the beautiful morning. Most didn't seem to recognize him. They simply said "thank you" as he placed yogurt cups on their plates and moved on. A handful of people shook his hand, though, and congratulated him on his accomplishments.

One of them was Ken Pierson, 44, who runs a tool-and-die shop in Janesville with his father. He made a point of introducing his two sons to the governor. Later, he said he thinks Walker's changes will help the state in the long run and the recall isn't justified.

"There's better things to do, better reasons to go after people. It's just too obnoxious for me," Pierson said. "I see (Walker's fiscal conservatism) working in the future. It has more to do with what's going to happen tomorrow, instead of `gimme, gimme, gimme."'

The recall represents the latest chapter in a knockdown, no-holds barred political battle that has consumed the state.

The fight began in February 2011 when Walker introduced the collective bargaining measure. Tens of thousands of people descended on the state Capitol to demonstrate against the plan and minority Democrats in the state Senate fled to Illinois in a futile attempt to block a vote.

Republicans who controlled the Legislature pushed the plan through anyway. Democrats have been looking for payback ever since.

They ousted two GOP state senators in recalls last August and gathered enough signatures on recall petitions this winter to force Walker and four other Republican officeholders into Tuesday's elections.

The race between Walker and Barrett, especially, has evolved into a national referendum on union power. Republicans across the country have rallied around the governor, helping him raise a jaw-dropping $31 million in campaign cash.

U.S. Rep. Paul Ryan, a Janesville Republican, and Republican National Committee Chairman Reince Priebus appeared a tea party rally in Caledonia, just outside Racine, Saturday morning and implored hundreds in the crowd to get as many people to the polls as they can on Tuesday. They said a Walker win would segue into defeat for President Barack Obama in Wisconsin in November.

"This is an election that will send shockwaves throughout America," Ryan told the crowd. "It is a momentum maker or a momentum breaker."



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Pentagon chief visits former US base in Vietnam

By Samuel P. Jacobs | Reuters â€" 

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Cops claim they were demoted for being Republicans

Six Long Island cops claim they were targeted by their commissioner for supporting Republican Party candidates in local elections last year.

Long Beach Police Commissioner Michael Tangney, a longtime Democrat, demoted the cops, cut their overtime, switched them to midnight shifts and even filed false internal charges against them for "political payback," the veteran officers claim in a $39 million lawsuit.

Tangney allegedly told one of the officers while demoting him, "It's just the way politics work in this town."

Officers James Canner, 44; Karl Hayes, 42; James McCormack, 55; John Radin, 53; Benjamin Tayne, 47; and Jose Miguez, 39, claim they turned to their union for help but that then-president Stefan Chernaski, another Democrat, ignored them.

Click for more from The New York Post.



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Syrian President Blames \'Outside Forces\' for Crisis

  • syria_annan_assad_meeting.jpg

    May 29, 2012: In this photo released by the Syrian official news agency SANA shows UN-Arab League Joint Special Envoy for Syria (JSE) Kofi Annan, fourth left, Norwegian Maj. Gen. Robert Mood, head of the U.N. observer team in Syria, third left, Syrian President Bashar Assad, third right, and Syrian Foreign Minister Walid Moallem, second right, attend a meeting in Damascus, Syria. International envoy Kofi Annan met Syrian President Bashar Assad on Tuesday following a massacre last week that killed more than 100 people and sparked widespread international condemnation against Damascus.AP/SANA

Syria's president says his country is facing a "real war" and he blames outside forces for driving the crisis.

President Bashar Assad is speaking to parliament Sunday as the country appears to be spiraling toward civil war.

He said the country is passing through its most critical stage since the end of colonialism.

His message was similar to previous speeches, in which he blamed terrorists for the country's uprising. The revolt began last March.

It's his first address since the massacre in Syria's central region of Houla that killed more than 100 people, nearly half of them children. U.N. investigators have said there are strong suspicions that pro-regime gunmen are responsible for at least some of the killings.

Activists say as many as 13,000 people have died in the violence. One year after the revolt began, the U.N. put the toll at 9,000, but hundreds more have died since.

Syria has long faced international isolation, but the Houla massacre has brought a new urgency to calls to end the crisis. A cease-fire plan brokered by international envoy Kofi Annan is violated by both sides every day. Fears also have risen that the violence could spread and provoke a regional conflagration.

Already clashes have broken out between pro- and anti-Syrian groups in northern Lebanon, with at least eight people killed late Friday and early Saturday, Lebanese security officials said.

With violence continuing despite nearly 300-strong U.N. observers on the ground in Syria, League chief Nabil Elaraby suggested Saturday that the monitors' mission shift into a peacekeeping one.

"What is needed today is not only observing and investigating but supervising that the violence stops," Elaraby told a meeting of Arab League foreign ministers in Qatar. "One of the alternatives could be amending the authorization regarding the observers so that they become a peacekeeping force."

Annan, who has been trying to salvage his six-point peace plan, warned that "the specter of all-out civil war, with a worrying sectarian dimension, grows by the day," in Syria, and added that the crisis is spilling over to neighboring countries, an apparent reference to Lebanon.

Washington has reached out to Syria's most important ally and protector, urging Russia to join a coordinated effort to resolve the deadly conflict.

Secretary of State Hillary Rodham Clinton discussed the situation with Russian Foreign Minister Sergei Lavrov in a telephone call on Saturday, a senior State Department official said.

"They both agreed that we have to work together," said the official, who provided details of the private discussion on condition of anonymity. "Her message to him was that we have to start working together to help Syrians with a serious political transition strategy."

Clinton said U.S. and Russian officials should engage diplomatically to come up with ideas in Moscow, Washington, New York and "wherever we need to," according to the official."

Russia has refused to support any move that could lead to foreign intervention in Syria, Moscow's last significant ally in the Middle East. Russia, along with China, has twice used its veto power to shield Syria from U.N. sanctions.



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Boats take to Thames for queen\'s jubilee flotilla

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Five bodies found in burned SUV in Ariz. desert

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Iran leader says sanctions deepen hatred of West

Iran's Supreme Leader says Western sanctions will not stop Tehran's progress but will only deepen hatred of the West in the hearts of the Iranian people.

Ayatollah Ali Khamenei delivered his remarks Sunday at the mausoleum of the founder of the Islamic Republic, Ayatollah Ruhollah Khomeini, at a ceremony marking the 23rd anniversary of his death.

Khamenei rejected as "lies" accusations by the U.S. and its allies that Iran is seeking to develop nuclear weapons. He also called Israel Iran's number one enemy.

Iran is currently engaged in talks with six world powers over its nuclear program. The six have demanded that Iran stop enriching uranium to levels they say could be upgraded to weapons-grade material more quickly. Tehran says recently toughened Western sanctions must be lifted in exchange.



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Syria president blames \'outside forces\'

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Queen to lead giant jubilee river pageant

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2 people dead after venomous spiders invade town

A town in India has suddenly been overrun by swarms of venomous spiders, leaving two people dead after being bitten.

It may sound like a B-grade horror movie, but residents of the town of Sadiya, in Assam state, say that on the evening of May 8 as they were celebrating a Hindu festival swarms of spiders suddenly appeared and attacked them, The Times of India reported.

Over the next few days two people -- a man, Purnakanta Buragohain, and an unnamed school boy -- died after being bitten by the spiders. Scores more turned up at the town's hospital with spider bites.

Local resident Jintu Gogoi spent a day in the hospital complaining of excruciating pain and nausea after being bitten. He said weeks later his finger was still blackened and swollen.

District authorities are also panicking -- and they are considering spraying the town with the insecticide DDT.

Locals say the most terrifying aspect is that spiders appear in swarms and their behavior is highly aggressive.

"It leaps at anything that comes close. Some of the victims claimed the spider latched on to them after biting. If that is so, it needs to be dealt with carefully. The chelicerae and fangs of this critter are quite powerful," head of the department of life sciences at Dibrugarh University Dr. L.R. Saikia said.

Teams of Indian arachnid experts have flocked to the town, hoping to identify the species, but so far they have drawn a blank.

They say it could be a tarantula, a black wishbone or even a funnel-web spider -- or it could be a whole new species.

One thing they agree on is that it is not native to the area as there is no record of venomous spiders in Assam. The black wishbone and funnel-web are native to Australia.

Researchers are also still running tests to find out the toxicity of the spiders' venom.

Dr. Anil Phatowali, superintendent of the town's hospital, said they had not administered antivenin as they could not be certain the spider was venomous at all.

He also pointed out other factors may have contributed to the two reported fatalities.

"All the bite patients first went to witch doctors, who cut open their wounds with razors, drained out blood and burnt it. That could have also made them sick," Phatowali said.



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2 people dead after venomous spiders invade town

A town in India has suddenly been overrun by swarms of venomous spiders, leaving two people dead after being bitten.

It may sound like a B-grade horror movie, but residents of the town of Sadiya, in Assam state, say that on the evening of May 8 as they were celebrating a Hindu festival swarms of spiders suddenly appeared and attacked them, The Times of India reported.

Over the next few days two people -- a man, Purnakanta Buragohain, and an unnamed school boy -- died after being bitten by the spiders. Scores more turned up at the town's hospital with spider bites.

Local resident Jintu Gogoi spent a day in the hospital complaining of excruciating pain and nausea after being bitten. He said weeks later his finger was still blackened and swollen.

District authorities are also panicking -- and they are considering spraying the town with the insecticide DDT.

Locals say the most terrifying aspect is that spiders appear in swarms and their behavior is highly aggressive.

"It leaps at anything that comes close. Some of the victims claimed the spider latched on to them after biting. If that is so, it needs to be dealt with carefully. The chelicerae and fangs of this critter are quite powerful," head of the department of life sciences at Dibrugarh University Dr. L.R. Saikia said.

Teams of Indian arachnid experts have flocked to the town, hoping to identify the species, but so far they have drawn a blank.

They say it could be a tarantula, a black wishbone or even a funnel-web spider -- or it could be a whole new species.

One thing they agree on is that it is not native to the area as there is no record of venomous spiders in Assam. The black wishbone and funnel-web are native to Australia.

Researchers are also still running tests to find out the toxicity of the spiders' venom.

Dr. Anil Phatowali, superintendent of the town's hospital, said they had not administered antivenin as they could not be certain the spider was venomous at all.

He also pointed out other factors may have contributed to the two reported fatalities.

"All the bite patients first went to witch doctors, who cut open their wounds with razors, drained out blood and burnt it. That could have also made them sick," Phatowali said.



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Political activists converge on Wisconsin for recall

Cowed by decades of brutal army rule, Myanmars population is not used to openly voicing opinionsCowed by decades of brutal army rule, Myanmars population is not used to openly voicing opinions, but as a taboo on political discussion wanes pollsters are stepping up to take the pulse of the nation.




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Lost wallaby found on rural Pennsylvania road

Pennsylvania authorities were searching for the owner of a runaway wallaby Saturday, after officials captured the animal on a rural road in the state's far northwest.

The Pennsylvania Game Commission said in a statement the native Australian marsupial -- which resembles a small kangaroo -- was tranquilized Wednesday afternoon after being found on a road near Cambridge Springs, Pa.

"My landlord saw it, so I went down and took a photo of it," former Game Commission biologist aide Sarah Dippold said.  "I forwarded the photo to the Game Commission's Northwest Region office."

The animal is currently being cared for at a licensed animal facility until its owner is identified.



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College student dies in 70 foot plunge from waterfall

A Utah college student died Saturday after falling about 70 feet while climbing a slippery rockface at a Utah County waterfall, south of Salt Lake City, Fox 13 reports.

Adam Perazzo, a 22-year-old Brigham Young University student from Nevada, was free climbing without safety gear when he slipped and fell.

Utah County sheriff's Sgt. Eldon Packer said Perazzo was with seven or eight friends at the time of the accident. Perazzo's friends attempted CPR, but he was declared dead at the scene after emergency officials arrived.

Click for more from Fox 13.

Newscore contributed to this report.



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China cracks down during Tiananmen anniversary

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US drones kill five militants in Pakistan

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Experimental drug keeps aggressive breast cancer at bay

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Drew Ties the Knot

  • Drew Engagement 640

    Nov. 15: Actress Drew Barrymore (R) and Will Kopelman (L) attend the Museum of Modern Art's fourth annual Film Benefit in New York. (REUTERS)

Drew Barrymore and her art dealer fiance Will Kopelman married Saturday at the actress' Montecito, Calif., home.

Among the guests at the wedding were Jimmy Fallon and his wife Nancy Juvonen, Barrymore's "Charlie's Angels" co-star Cameron Diaz and actress Busy Philipps, People magazine reported.

Reese Witherspoon and her husband Jim Toth were also in attendance, according to E! Online.

Barrymore wore a Chanel gown -- not surprising as Kopelman's father is a former CEO of Chanel. Kopelman, 34, also wore a suit by the designer.

A rabbi officiated at the ceremony, which was "a classic, simple, very pretty, garden-inspired wedding," a source told People.

Friends told People that Barrymore is "ready for a quieter, more family-oriented life."

Despite not commenting publicly on her impending motherhood, Barrymore has been sporting an ever-growing baby bump in recent months.

Kopelman popped the question while the couple vacationed in Sun Valley, Idaho, in January.

The 37-year-old actress and Kopelman began dating last February.

Barrymore, who came to fame in 1982 as a child-star in "E.T.," has been married twice before.

Her first marriage to Welsh bar owner Jeremy Thomas lasted from March 20 to April 28, 1994.

She later wed comedian Tom Green on July 7, 2001, but the couple filed for divorce later that year.

Barrymore had also been romantically linked with The Strokes' drummer Fabrizio Moretti and actor Justin Long.



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Joe Biden\'s daughter marries doctor in Delaware

Phoenix police have arrested a woman who allegedly drove off after forgetting that her 5-week-old baby was in a car seat on the roof of her vehicle.

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US strike kills 10 suspected militants in Pakistan

Pakistani officials say an American drone strike in the frontier tribal areas has killed 10 suspected militants.

Two Pakistani intelligence officials say four missiles were fired at the village of Mana Raghzai near the border with Afghanistan on Sunday morning.

At the time of the attack, suspected militants were gathered to offer condolences to the brother of a militant commander killed during an American unmanned drone attack on Saturday.

Pakistan has repeatedly asked the U.S. to stop the drone attacks. But the U.S. has pushed ahead with the drone program that it considers vital to battling Al Qaeda and the Taliban.



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5 bodies found in burned vehicle in Arizona

  • ArizinaBurnedBodies.JPG

    June 2, 2012: Police say five dead bodies were found burned inside this vehicle in Pinal County's Vekol Valley area, west of Casa Grande, N.M.AP

Five bodies burned beyond recognition have been found inside the shell of a charred sport utility vehicle in the Arizona desert, and Pinal County Sheriff Paul Babeu said Saturday the case is likely connected to drug cartel violence.

Only 70 miles from the U.S.-Mexico border, Pinal County is concerned about the extent of the violence, Babeu said.

"This is pretty significant," he said of the latest homicide investigation. "Given all these indicators, you don't have to be a homicide detective to add up all this information."

Pinal County deputies were involved in more than 350 high-speed pursuits last year, and Babeu said most of those involved cartel members. There have been shootings, the bodies of murder victims have been left in the desert and just this week, several loads of drugs were confiscated, he said.

"This happens far too often and usually our involvement is just a small percentage of what really goes on," the sheriff said. "Is it concerning? Is it troubling? Yes it is."

The latest case started around 4:30 a.m. in the Vekol Valley area when a white Ford Expedition was spotted by a Border Patrol agent. The vehicle disappeared despite an effort by federal and local authorities to track it down. Why the vehicle drew attention is unclear.

At daybreak, an agent spotted tracks leading from Interstate 8 into the desert. The vehicle that left the tracks had apparently launched off the highway, going airborne for a short distance before landing in the desert. The tracks continued on for a couple of miles.

Agents could see the smoldering vehicle from a distance through binoculars.

They approached with extinguishers. Inside, they found the bodies -- one in the rear passenger seat and four lying in the back cargo compartment. The front seats were empty, Babeu said.

The bodies were so badly burned that investigators could not immediately determine their gender or ethnicity. While it's unclear whether the victims were from Mexico, the sheriff's office has notified the Mexican Consulate.

Babeu said investigators will try to determine whether the victims were dead before the SUV was set ablaze or whether they were alive when the fire was started.

"Clearly these people were murdered, but we don't know the manner of death," he said.

The sheriff said the extent of the violence, particularly in the western part of the county -- about 35 miles south of Phoenix -- is a concern. He said it's more evidence that drug smuggling north of the border continues to be significant and has not subsided.



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Panetta arrives at former US base in Vietnam- US will shift warships to Asia-Pacific strategy

  • PanettaAsia.JPG

    June 3, 2012: U.S. Secretary of Defense Leon Panetta, second from left, walks with Commander Air Power Generation Command Col. Sarbjit Singh, left, Defense and Naval Attache for Singapore Capt. John Wood, second from right, and Singapore Defense Attache to the U.S. Brig Gen. Chee Wee Tan before departing Paya Lebar Airfeild, Singapore.AP

U.S. Defense Secretary Leon Panetta has arrived at a former U.S. air and naval base at Cam Ranh Bay, Vietnam, becoming the most senior American official to go there since the war ended.

Panetta says he hopes to encourage efforts with Vietnam to locate and identify more of the U.S. war dead who are still missing.

He plans to visit the USNS Richard E. Byrd, a cargo ship operated by the Navy's Military Sealift Command. The ship has a largely civilian crew and is used to move military supplies to U.S. forces around the world.

The U.S. military's Joint POW/MIA Accounting Command has six recovery teams and two investigative teams in Vietnam searching for troop remains. There are about 1,200 unaccounted for service members believed to be in Vietnam.



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\'Smart Bomb\' Drug Attacks Breast Cancer, Study Says

Doctors have successfully dropped the first "smart bomb" on breast cancer, using a drug to deliver a toxic payload to tumor cells while leaving healthy ones alone.

In a key test involving nearly 1,000 women with very advanced disease, the experimental treatment extended by several months the time women lived without their cancer getting worse, doctors planned to report Sunday at a cancer conference in Chicago.

More importantly, the treatment seems likely to improve survival; it will take more time to know for sure. After two years, 65 percent of women who received it were still alive versus 47 percent of those in a comparison group given two standard cancer drugs.

That margin fell just short of the very strict criteria researchers set for stopping the study and declaring the new treatment a winner, and they hope the benefit becomes more clear with time. In fact, so many women on the new treatment are still alive that researchers cannot yet determine average survival for the group.

"The absolute difference is greater than one year in how long these people live," said the study's leader, Dr. Kimberly Blackwell of Duke University. "This is a major step forward."

A warning to hopeful patients: the drug is still experimental, so not available yet. Its backers hope it can reach the market within a year.

The treatment builds on Herceptin, the first gene-targeted therapy for breast cancer. It is used for about 20 percent of patients whose tumors overproduce a certain protein.

Researchers combined Herceptin with a chemotherapy so toxic that it can't be given by itself, plus a chemical to keep the two linked until they reach a cancer cell where the poison can be released to kill it.

This double weapon, called T-DM1, is the "smart bomb," although it's actually not all that smart -- Herceptin isn't a homing device, just a substance that binds to breast cancer cells once it encounters them.

Doctors tested T-DM1 in 991 women with widely spread breast cancer that was getting worse despite treatment with chemotherapy and ordinary Herceptin. They were given either T-DM1 infusions every three weeks or infusions of Xeloda plus daily Tykerb pills -- the only other treatments approved for such cases.

The median time until cancer got worse was nearly 10 months in the women given T-DM1 versus just over 6 months for the others. That is about the same magnitude of benefit initially seen with Herceptin, which later proved to improve overall survival, too, Blackwell said.

T-DM1 caused fewer side effects than the other drugs did. Some women on T-DM1 had signs of liver damage and low levels of factors that help blood clot, but most did not have the usual problems of chemotherapy.

"People don't lose their hair, they don't throw up. They don't need nausea medicines, they don't need transfusions," said Blackwell, who has consulted in the past for Genentech, the study's sponsor.

"The data are pretty compelling," said Dr. Michael Link, a pediatric cancer specialist at Stanford University who is president of the American Society of Clinical Oncology, the group hosting the Chicago conference where the results were being presented.

"It's sort of a smart bomb kind of therapy, a poison delivered to the tumor ... and not a lot of other collateral damage to other organs," he said.

Dr. Louis Weiner, director of Georgetown Lombardi Comprehensive Cancer Center, said the results strongly suggest T-DM1 improves survival. It delivers more drug directly to tumors with less side effects, "a clear advance," he said.

Denise Davis, 51, a customer service representative at a propane company, was diagnosed three years ago with breast cancer that had spread to her liver and bones. Since February of last year, the Lynchburg, Va., woman has made the two-hour trip to Duke in Durham, N.C., every three weeks to get infusions of T-DM1.

"I call it `Herceptin-plus,"' she said. Scans every six weeks show "everything is still shrinking or stable," she said. "Right now, I'm feeling pretty good about it. The only way I'd feel a little better is if it took care of everything, but I'll take what I can get."

Genentech, part of the Swiss company Roche, plans to seek approval later this year to sell the drug in Europe and the United States. Another company, ImmunoGen Inc., made the technology combining the drugs.

Genentech says the price of T-DM1 has not been determined. Herceptin costs more than $4,000 a month plus whatever doctors charge to infuse it. Herceptin's U.S. patent doesn't expire until 2019.



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Panetta arrives at former U.S. base in Vietnam

By LOLITA C. BALDOR | Associated Press â€" 

Article from YAHOO NEWS


New Mexico Braces for More Flames

  • Western Wildfires_Pata.jpg

    May 29, 2012: In this Tuesday photo provided by the U.S. Forest Service, a firefighter walks along a burn out line as part of an effort to contain the nation's largest wildfire in the Gila National Forest in New Mexico.

The more than 1,200 firefighters who are battling the nation's largest wildfire in rugged mountains and canyons of southwestern New Mexico are racing to build lines to corral the massive blaze.

The fire had charred more than 354 square miles by Saturday morning, and crews were bracing for more dry and windy conditions.

Fire information officer Lee Bentley says the focus is on the western edge of the Whitewater-Baldy fire.

The fire is expected to start backing down the mountains east of the community of Glenwood, and officials say residents should expect to see more smoke and flames as firefighters continue their backburn operations.

Bentley says gusts could reach close to 30 mph Saturday, resulting in active to extreme fire behavior.

The fire is about 15 percent contained.

It has charred 227,000 acres of the Gila National Forest and a dozen cabins and several outbuildings have been destroyed.



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